Gadolinium Toxicity

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My experience with Gadolinium urine testing

My first urine test for Gadolinium was not done until a full two years after my last dose of contrast.  Part of the delay was because I did not know about the test until almost 18 months had gone by.

I wanted my first test to be performed by Mayo Clinic Labs; however, I had difficulty making that happen.  The lab affiliated with the medical clinic where most of my doctors are located told me that they could not do any testing for heavy metals or send specimens out to another lab for the testing.  But I finally found a way around that problem.

The lab at our local hospital regularly sends specimens to Mayo Clinic in Rochester, Minnesota.  (more…)

Gadolinium-Associated Plaques (GAP) in a patient without renal disease.

On November 12, 2014, an article was published online about a new condition called Gadolinium-Associated Plaques or GAP.  The JAMA Dermatology article by Gathings, Reddy, Santa Cruz, and Brodell is titled, “Case Report/Case Series, Gadolinium-Associated Plaques – A New, Distinctive Clinical Entity”.  The full-article is not freely available online at this time; however, the abstract can be found at http://dx.doi.org/10.1001/jamadermatol.2014.2660.

While this case series reports on only 2 patients, its findings are especially significant for patients with normal renal (kidney) function.  Both patients had erythematous plaques which were determined to be sclerotic bodies in various stages of calcification.  Previously these sclerotic bodies were thought to be associated with NSF (Nephrogenic Systemic Fibrosis) in patients with chronic renal disease after exposure to a Gadolinium-based Contrast Agent (GBCA).  The significance of this case series is that neither patient had NSF; while one patient did have renal disease, the other patient did not.  (more…)