Gadolinium Toxicity

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Study reports elevated cytokine levels in patients with confirmed gadolinium retention

Results of a study to determine whether individuals with proposed gadolinium deposition disease (GDD) have elevated serum levels of pro-inflammatory and pro-fibrotic cytokines were recently published. GDD has been reported in patients with normal renal function after MRIs with a gadolinium-based contrast agent (GBCA). The study by Maecker et al., “An initial investigation of serum cytokine levels in patients with gadolinium retention”, also sought to determine whether specific cytokines are correlated with certain symptoms considered to be characteristic of GDD.  The study involved 24 participants who were recruited between May 2016 and June 2017 and met the proposed GDD diagnostic criteria. Some of the participants were recruited from our MRI-Gadolinium-Toxicity support group.  A control group of 64 subjects provided serum samples before their flu vaccination.  Serum cytokine levels were obtained with Luminex serum cytokine assay using eBiosciences/Affymetrix human 62-plex kits.

In patients who had retained gadolinium, serum levels of 14 cytokines, including 9 pro-inflammatory cytokines, were “statistically significantly elevated” compared to controls (p ≤ 0.05).  (more…)

Pain from Peripheral Neuropathy can be caused by metals like Gadolinium

When we conducted our Symptom Survey early in 2014, the one chronic symptom that everyone reported was “Pain”.  Some identified it as being an ache with dull, continuous pain, while others described it as burning, numbness, tingling, or prickling sensations (paresthesia), or as deep bone pain, or electric-like feelings.  The location of the pain was primarily in the extremities, followed by the hips, joints, and ribs.

From my own experience, I can tell you that I always have some level of pain even with taking prescription medication.  While stronger medications might make me feel pain free, I prefer to live with a tolerable level of pain rather than feel over-medicated.

From what I have read, it seems that most of our pain is the result of damage to our nervous system. (more…)

Small Fiber Sensory Neuropathy from Gadolinium Toxicity

As you will see, I have been diagnosed as having Small Fiber Sensory Neuropathy, and the possible cause would appear to be my Gadolinium Toxicity.   This posting explains a bit about Small Fiber Sensory Neuropathy.

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