Gadolinium Toxicity

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July 21, 2017 – European Medical Authority takes action on Linear Contrast Agents.  Read all about it.

March 10, 2017 – European group recommends to stop using 4 linear GBCAs Read all about it.

February 27, 2017 – New Study Reports Gadolinium Retention in 70 Cases with Normal Kidney Function. Read all about it.

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Gadolinium-Associated Plaques (GAP) in a patient without renal disease.

On November 12, 2014, an article was published online about a new condition called Gadolinium-Associated Plaques or GAP.  The JAMA Dermatology article by Gathings, Reddy, Santa Cruz, and Brodell is titled, “Case Report/Case Series, Gadolinium-Associated Plaques – A New, Distinctive Clinical Entity”.  The full-article is not freely available online at this time; however, the abstract can be found at http://dx.doi.org/10.1001/jamadermatol.2014.2660.

While this case series reports on only 2 patients, its findings are especially significant for patients with normal renal (kidney) function.  Both patients had erythematous plaques which were determined to be sclerotic bodies in various stages of calcification.  Previously these sclerotic bodies were thought to be associated with NSF (Nephrogenic Systemic Fibrosis) in patients with chronic renal disease after exposure to a Gadolinium-based Contrast Agent (GBCA).  The significance of this case series is that neither patient had NSF; while one patient did have renal disease, the other patient did not.  (more…)

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