Gadolinium Toxicity

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Breaking News

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March 10, 2017 - European group recommends to stop using 4 linear GBCAs Read all about it.

February 27, 2017 - New Study Reports Gadolinium Retention in 70 Cases with Normal Kidney Function. Read all about it.

As part of our Advocacy efforts to draw attention to the problem of Gadolinium retention and the effects of Gadolinium Toxicity, we have conducted our own research.

New Research in 2017

Our paper titled Gadolinium Retention from Contrast MRIs in 70 Cases with Normal Renal Function – 24-hour Urine Test Results, released in February 2017, presents what we believe to be the most comprehensive reporting of retained gadolinium as evidenced by gadolinium concentration in 24-hour urine collections.  The 120 test results demonstrate that, contrary to what GBCA product labeling indicates should occur, the gadolinium in our study group did not clear the body within a few days. This finding conflicts with what most practitioners believe will happen. Comparison of results based on the number of contrast MRIs received indicates that cases with higher numbers of contrast administrations have higher levels of chronic toxicity than cases with smaller numbers of contrast administrations. (February 27, 2017)

Earlier Research

An Overview of Gadolinium Toxicity is a literature review of over 100 medical and scientific papers that contain information related to the toxicity of retained Gadolinium from Gadolinium-based Contrast Agents.  It can be shared with medical professionals to help them understand that all patients are at risk of developing varying degrees of Gadolinium Toxicity as a result of contrast-enhanced MRIs and MRAs. (March 27, 2013)

The Group Self-Study of Gadolinium Retention from Contrast MRIs reports on the toxic levels of Gadolinium found in the urine of 13 participants.  This is the first study of this information that has ever been released.   All the participants had normal kidney function at the time of their contrast procedures. (October 1, 2013)

The Survey of the Chronic Effects of Retained Gadolinium from Contrast MRIs reports on the symptoms experienced by a group of patients with elevated levels of Gadolinium in their urine and updates the Gadolinium Retention information published in the second paper.  The results show high levels of commonality in the participants’ chronic symptoms of Gadolinium Toxicity that are consistent with what is known about NFD/NSF patients’ symptoms and affected body systems. (April 2, 2014)


4 Comments

  1. Alison says:

    Does gadolinium store itself in every single person that has had it. I am having all kinds of problems and don’t know what to attribute to what…
    Who can I explain my symptoms to?

    • Hubbs G says:

      The storage of gadolinium in persons receiving a contrast MRI is the subject of new research since evidence was found in 2014 of this occurring in people with good kidney function. So it would appear that it’s not well understood at this time.
      If you read the Risk Factors for gadolinium Toxicity on this website (https://gadoliniumtoxicity.com/background/risk-factors/) you will see that Dr. Abraham estimated that 1% of the gadolinium in the contrast agent is retained, most likely in the bones. But the quantitative details of this have not been determined.
      Since doctors generally are not aware of issues related to Gadolinium Toxicity, the best place for you to understand if your symptoms might be related is the MRI Gadolinium Toxicity Support Group at https://groups.yahoo.com/neo/groups/MRI-Gadolinium-Toxicity/info .

  2. Jennifer says:

    How long does it take for gadolinium to be cleared from the body? It was used for an MRA, so injected into the joint.

    • Hubbs G says:

      No one really knows. Personally my last contrast was 7 years ago, and the tests for Gd in my urine are still nearly double the Mayo Range that should apply anytime after 96 hours. Even people who have reached a “Not Detectable” result with an unprovoked urine test will often have a provoked result of 10 times the Mayo range, so there is plenty still in their tissues. I wish we had a better answer.

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